Abstract Background The presence of bone metastases has excluded participation of prostate cancer patients in exercise intervention studies to date and is also a relative contraindication to supervised exercise in the community setting because of concerns of fragility fracture.However, this group of patients often have developed significant muscle
Hamartin: An Endogenous Neuroprotective Molecule Induced by Hypoxic Preconditioning
Hypoxic/ischemic preconditioning (HPC/IPC) is an innate neuroprotective mechanism in which a number of endogenous molecules are known to be involved.Tuberous sclerosis complex 1 (TSC1), also known as hamartin, is thought to be one such molecule.It is also known that hamartin is involved as a target in the rapamycin (mTOR) signaling pathway, which f
Emerging Piezoelectric Sonosensitizer for ROS-Driven Sonodynamic Cancer Therapy
As a non-invasive modality, sonodynamic therapy (SDT) offers several advantages in cancer treatment, including deep tissue penetration and precise spatiotemporal control, Pourover Coffee Machines resulting from the interplay between low-intensity ultrasound and sonosensitizers.Piezoelectric materials, known for their remarkable capacity of intercon
The measurement of Physical Workload and Mental Workload Level of Medical Personnel
As the primary health reference center, a hospital is required to provide excellent quality services to each patient.The impact of the extreme physical and mental workload cause negligence in activities.It affects the quality of services provided by medical personnel.This study investigated the level of mental workload and physical workload in medi